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PDF) WSG ADAPT - adjuvant dynamic marker-adjusted personalized therapy trial  optimizing risk assessment and therapy response prediction in early breast  cancer: Study protocol for a prospective, multi-center, controlled,  non-blinded, randomized ...
PDF) WSG ADAPT - adjuvant dynamic marker-adjusted personalized therapy trial optimizing risk assessment and therapy response prediction in early breast cancer: Study protocol for a prospective, multi-center, controlled, non-blinded, randomized ...

Adaptive design (medicine) - Wikipedia
Adaptive design (medicine) - Wikipedia

Chemotherapy de-escalation using an 18F-FDG-PET-based pathological  response-adapted strategy in patients with HER2-positive early breast cancer  (PHERGain): a multicentre, randomised, open-label, non-comparative, phase 2  trial - The Lancet Oncology
Chemotherapy de-escalation using an 18F-FDG-PET-based pathological response-adapted strategy in patients with HER2-positive early breast cancer (PHERGain): a multicentre, randomised, open-label, non-comparative, phase 2 trial - The Lancet Oncology

ADAPT HER2+/HR+ trial design. HER2+/HR+ patients receive either T-DM1... |  Download Scientific Diagram
ADAPT HER2+/HR+ trial design. HER2+/HR+ patients receive either T-DM1... | Download Scientific Diagram

Neoadjuvant treatment of HER2-positive breast cancer: should therapy differ  based on hormone receptor status? - Nadia Harbeck, 2018
Neoadjuvant treatment of HER2-positive breast cancer: should therapy differ based on hormone receptor status? - Nadia Harbeck, 2018

Case 3: POETIC and ADAPT Trials in HR+ High-Risk Breast Cancer
Case 3: POETIC and ADAPT Trials in HR+ High-Risk Breast Cancer

OncoAlert on X: "The #OncoAlertTopTweet 🚨Day5⃣of #ESMO21 Tweet  @Dr_Ivanoncologo Dr. Harbeck: Predictive impact of biomarkers🎯on pCR and  survival after de-escalated neoadjuvant T-DM1 w/ or w/o endocrine therapy  (ET) vs Trastuzumab🧪+ ET in
OncoAlert on X: "The #OncoAlertTopTweet 🚨Day5⃣of #ESMO21 Tweet @Dr_Ivanoncologo Dr. Harbeck: Predictive impact of biomarkers🎯on pCR and survival after de-escalated neoadjuvant T-DM1 w/ or w/o endocrine therapy (ET) vs Trastuzumab🧪+ ET in

Immunotherapy for early triple negative breast cancer: research agenda for  the next decade | npj Breast Cancer
Immunotherapy for early triple negative breast cancer: research agenda for the next decade | npj Breast Cancer

WSG ADAPT – adjuvant dynamic marker-adjusted personalized therapy trial  optimizing risk assessment and therapy response prediction in early breast  cancer: study protocol for a prospective, multi-center, controlled,  non-blinded, randomized, investigator ...
WSG ADAPT – adjuvant dynamic marker-adjusted personalized therapy trial optimizing risk assessment and therapy response prediction in early breast cancer: study protocol for a prospective, multi-center, controlled, non-blinded, randomized, investigator ...

Cancers | Free Full-Text | ERBB2 mRNA Expression and Response to  Ado-Trastuzumab Emtansine (T-DM1) in HER2-Positive Breast Cancer
Cancers | Free Full-Text | ERBB2 mRNA Expression and Response to Ado-Trastuzumab Emtansine (T-DM1) in HER2-Positive Breast Cancer

De-escalated neoadjuvant pertuzumab plus trastuzumab therapy with or  without weekly paclitaxel in HER2-positive, hormone receptor-negative,  early breast cancer (WSG-ADAPT-HER2+/HR–): survival outcomes from a  multicentre, open-label, randomised, phase 2 ...
De-escalated neoadjuvant pertuzumab plus trastuzumab therapy with or without weekly paclitaxel in HER2-positive, hormone receptor-negative, early breast cancer (WSG-ADAPT-HER2+/HR–): survival outcomes from a multicentre, open-label, randomised, phase 2 ...

De-escalated neoadjuvant paclitaxel, dual HER2 blockade effective in breast  cancer subtype
De-escalated neoadjuvant paclitaxel, dual HER2 blockade effective in breast cancer subtype

Frontiers | Management of HER2-Positive Early Breast Cancer in Italy: A  Maze Presenting Opportunities and Challenges
Frontiers | Management of HER2-Positive Early Breast Cancer in Italy: A Maze Presenting Opportunities and Challenges

Metastatic triple negative breast cancer adapts its metabolism to  destination tissues while retaining key metabolic signatures | PNAS
Metastatic triple negative breast cancer adapts its metabolism to destination tissues while retaining key metabolic signatures | PNAS

Using Neoadjuvant Endocrine Therapy to Understand Resistance in Breast  Cancer
Using Neoadjuvant Endocrine Therapy to Understand Resistance in Breast Cancer

CONSORT diagram. Disposition of patients in the ADAPT (Adjuvant Dynamic...  | Download Scientific Diagram
CONSORT diagram. Disposition of patients in the ADAPT (Adjuvant Dynamic... | Download Scientific Diagram

Neoadjuvant and adjuvant treatment of patients with HER2-positive early breast  cancer - ScienceDirect
Neoadjuvant and adjuvant treatment of patients with HER2-positive early breast cancer - ScienceDirect

Molecular and protein markers for clinical decision making in breast cancer:  Today and tomorrow - ScienceDirect
Molecular and protein markers for clinical decision making in breast cancer: Today and tomorrow - ScienceDirect

S5-03 Final analysis of WSG-ADAPT HER2+/HR+ phase II trial: Efficacy,  safety, and predictive markers for 12-weeks of neoadjuvant
S5-03 Final analysis of WSG-ADAPT HER2+/HR+ phase II trial: Efficacy, safety, and predictive markers for 12-weeks of neoadjuvant

The Evolving Role of Neoadjuvant Therapy for Operable Breast Cancer in:  Journal of the National Comprehensive Cancer Network Volume 20 Issue 6  (2022)
The Evolving Role of Neoadjuvant Therapy for Operable Breast Cancer in: Journal of the National Comprehensive Cancer Network Volume 20 Issue 6 (2022)

Cancers | Free Full-Text | Immune Markers and Tumor-Related Processes  Predict Neoadjuvant Therapy Response in the WSG-ADAPT HER2-Positive/Hormone  Receptor-Positive Trial in Early Breast Cancer
Cancers | Free Full-Text | Immune Markers and Tumor-Related Processes Predict Neoadjuvant Therapy Response in the WSG-ADAPT HER2-Positive/Hormone Receptor-Positive Trial in Early Breast Cancer

Advanced hybrid closed loop therapy versus conventional treatment in adults  with type 1 diabetes (ADAPT): a randomised controlled study - The Lancet  Diabetes & Endocrinology
Advanced hybrid closed loop therapy versus conventional treatment in adults with type 1 diabetes (ADAPT): a randomised controlled study - The Lancet Diabetes & Endocrinology

ADAPT Triple Negative trial design. Triple negative (HER2-/HR-)... |  Download Scientific Diagram
ADAPT Triple Negative trial design. Triple negative (HER2-/HR-)... | Download Scientific Diagram

Evidence-based guidelines for managing patients with primary ER+ HER2− breast  cancer deferred from surgery due to the COVID-19 pandemic | npj Breast  Cancer
Evidence-based guidelines for managing patients with primary ER+ HER2− breast cancer deferred from surgery due to the COVID-19 pandemic | npj Breast Cancer

De-escalated neoadjuvant pertuzumab plus trastuzumab therapy with or  without weekly paclitaxel in HER2-positive, hormone receptor-negative,  early breast cancer (WSG-ADAPT-HER2+/HR–): survival outcomes from a  multicentre, open-label, randomised, phase 2 ...
De-escalated neoadjuvant pertuzumab plus trastuzumab therapy with or without weekly paclitaxel in HER2-positive, hormone receptor-negative, early breast cancer (WSG-ADAPT-HER2+/HR–): survival outcomes from a multicentre, open-label, randomised, phase 2 ...

Susan G. Komen on X: "WSG ADAPT HR-/HER2+ phase II trial showed improved  pathological complete response (pCR) and survival in patients treated by  #de-escalated chemotherapy, pertuzumab, and trastuzumab. Early pCR strongly  associated
Susan G. Komen on X: "WSG ADAPT HR-/HER2+ phase II trial showed improved pathological complete response (pCR) and survival in patients treated by #de-escalated chemotherapy, pertuzumab, and trastuzumab. Early pCR strongly associated

ADAPT Umbrella trial design. Patients are included in the trial based... |  Download Scientific Diagram
ADAPT Umbrella trial design. Patients are included in the trial based... | Download Scientific Diagram